File:DE landscape.png
Size of this preview: 957 × 562 pixels. Other resolution: 330 × 194 pixels.
Original file (957 × 562 pixels, file size: 327 KB, MIME type: image/png)
Summary
| Description |
English: Performing multiple rounds of directed evolution is useful not only because a new library of mutants is created in each round but also because each new library uses better mutants as templates. The experiment is analogous to climbing a hill on a 'fitness landscape' where elevation represents the desired property. The goal is to reach the summit, which represents the best achievable mutant. Each round of selection samples mutants on all sides of the starting template (1) and selects the mutant with the highest elevation, thereby climbing the hill. This is repeated until a local summit is reached (2). |
| Date | |
| Source | Thomas, Shafee, (2014). "Evolvability of a viral protease: experimental evolution of catalysis, robustness and specificity". PhD Thesis. University of Cambridge. |
| Author | Thomas Shafee |
Licensing
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 00:29, 14 December 2014 | | 957 × 562 (327 KB) | Evolution and evolvability | increased axis title size |
| 00:15, 14 December 2014 |  | 957 × 562 (282 KB) | Evolution and evolvability | User created page with UploadWizard |
File usage
There are no pages that use this file.
Global file usage
The following other wikis use this file:
- Usage on cs.wikipedia.org
- Usage on en.wikipedia.org
- Usage on fr.wikipedia.org
- Usage on gl.wikipedia.org
- Usage on pt.wikipedia.org
- Usage on sk.wikipedia.org
